Genome Summary #3 Chapter 3 - History

     Dr. Archibald Garrod is introduced in the book. He published an accurate hypothesis in 1902 called the "inborn errors of metabolism." He thought that each gene produced one chemical catalyst, and the inborn mistakes were caused by genetic mutations, and proteins manage practically every function of the body. Garrod's theory did not resurface until thirty five years later though. Mendel and Darwin's theory of "the atomic theory of biology" and natural selection, respectively, were combined in 1918. Discoveries about mutations showed that genes were recipes for proteins and mutations were "altered proteins made by altered genes". Watson and Crick discovered the structure of DNA. Crick also discovered the twenty- three words that the genome uses.